International Alliance for COVID-19 Community Response
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Handbook of COVID-19 Prevention and Treatment

Issuing time:2020-03-19 20:53Author:马云公益基金会、阿里巴巴公益基金会、浙江大学附属第一医院Source:Global MediXchange for Combating COVID-19Link:



This is an unprecedented global war, and mankind is facing the same enemy, the novel coronavirus. And the first battlefield is the hospital where our soldiers are the medical workers.

To ensure that this war can be won, we must first make sure that our medical staff is guaranteed sufficient resources, including experience and technologies. Also, we need to make sure that the hospital is the battleground where we eliminate the virus, not where the virus defeats us.

Therefore, the Jack Ma Foundation and Alibaba Foundation have convened a group of medical experts who have just returned from the frontlines of fighting the pandemic. With the support of The First Affiliated Hospital, Zhejiang University School of Medicine (FAHZU), they quickly published a guidebook on the clinical experience of how to treat this new coronavirus. The treatment guide offers advice and reference against the pandemic for medical staff around the world who are about to join the war.

My special thanks goes out to the medical staff from FAHZU. While taking huge risks in treating COVID-19 patients, they recorded their daily experience which is reflected in this Handbook. Over the past 50 days, 104 confirmed patients have been admitted to FAHZU, including 78 severe and critically ill ones. Thanks to the pioneering efforts of medical staff and the application of new technologies, to date, we have witnessed a miracle. No staff were infected, and there were no missed diagnosis or patient deaths.

Today, with the spread of the pandemic, these experiences are the most valuable sources of information and the most important weapon for medical workers on the frontline. This is a brand-new disease, and China was the first to suffer from the pandemic. Isolation, diagnosis, treatment, protective measures, and rehabilitation have all started from scratch. WE hope that this Handbook can provide doctors and nurses in other affected areas valuable information so they don't have to enter the battlefield alone.

This pandemic is a common challenge faced by mankind in the age of globalization. At this moment, sharing resources, experiences and Lessons, regardless of who you are, is our only chance to win. The real remedy for this pandemic is not isolation, but cooperation.

This war has just begun.


Part One Prevention and Control Management

I. Isolation Area Management1

II. Staff Management4

III. COVID-19 Related Personal Protection Management5

IV. Hospital Practice Protocols during COVID-19 Epidemic6

V. Digital Support for Epidemic Prevention and Control16

Part Two Diagnosis and Treatment

I. Personalized, Collaborative and Multidisciplinary Management18

II. Etiology and Inflammation Indicators19

III. Imaging Findings of COVID-19 Patients   21

IV Application of Bronchoscopy in the Diagnosis and Management of COVID-19 Patients22

V Diagnosis and Clinical Classification of COVID-1922

VI. Antiviral Treatment for Timely Elimination of Pathogens23

VII. Anti-shock and Anti-hypoxemia Treatment24

VIII. The Rational Use of Antibiotics to Prevent Secondary Infection29

IX. The Balance of Intestinal Microecology and Nutritional Support30

X. ECMO Support for COVID-19 Patients32

XI. Convalescent Plasma Therapy for COVID-19 Patients35

XII. TCM Classification Therapy to Improve Curative Efficacy.36

XIII. Drug Use Management of COVID-19 Patients37

XIV. Psychological Intervention for COVID-19 Patients41

XV. Rehabilitation Therapy for COVID-19 Patients42

XVI. Lung Transplantation in Patients with COVID-1944

XVII. Discharge Standards and Follow-up Plan for COVID-19 Patients45

Part Three Nursing

I. Nursing Care for Patients Receiving High-Flow Nasal Cannula (HFNC) Oxygen Therapy.47

II. Nursing Care in Patients with Mechanical Ventilation47

III. Daily Management and Monitoring of ECMO (Extra Corporeal Membrane Oxygenation)49

IV. Nursing Care of ALSS (Artificial Liver Support System)50

V. Continuous Renal Replacement Treatment (CRRT) Care51

VI. General Care52


I. Medical Advice Example for COVID-19 Patients53

II. Online Consultation Process for Diagosis and Treatment57

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